rSEA - Simultaneous Enrichment Analysis
SEA performs simultaneous feature-set testing for (gen)omics data. It tests the unified null hypothesis and controls the family-wise error rate for all possible pathways. The unified null hypothesis is defined as: "The proportion of true features in the set is less than or equal to a threshold." Family-wise error rate control is provided through use of closed testing with Simes test. There are some practical functions to play around with the pathways of interest.
Last updated 10 months ago
3.70 score 10 scripts 464 downloadsrOCEAN - Two-Way Feature Set Testing for Multi-Omics
For any two way feature-set from a pair of pre-processed omics data, pairwise-TDP, Column-TDP and row-TDP are calculated. Due to embeded closed testing procedure, the choice of feature-sets can be changed infinite times and even after seeing the data withuot any change in type I error rate. For more details refer to the refrence article.
Last updated 5 months ago
3.30 score 2 scripts 491 downloads